Well, relating this to an other thread, if you alter the chemistry or structure of someone's brain through trauma, or hell, even through simply growing up and becoming an adult, you fundamentally change the "person". Even though we hold the same DNA we did as children, our brains have changed so much that it is only a technicality that we are considered the same individual we were when we were 5 years old, or however old we want to arbitrarily pick.
Similarly, you get a blow sufficiently damaging, or experience hypoxemia for a sufficient duration (3 - 5 minutes), and you will experience brain damage. Or you have a stroke or some other event which causes a non-fatal ischemia and necrosis of brain tissue. Either way, these events can lead to complete changes in personality, behaviour, memory, etc. You can become a totally different person through brain damage.
So, if simply changes to brain structure or chemistry are able to bring about a very dramatic change in personality, how is it that we might expect complete destruction of our brain to enable us to pass on to a new life with our "person" being intact? It is clear that who were are is intrinsically linked to our brains, and yet when we die our brains are destroyed. I do not see any reason to suspect that we would be able to survive death via an unseen "soul" given what we know.
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