In another thread on this topic, Atranox had a good post.
Originally Posted by Atranox
Do not confuse the PhysX engine with GPU-accelerated PhysX.
GPU-acceleration on PhysX requires an NVIDIA card for decent performance and full effects, while the engine itself does not as it runs exclusively on the CPU regardless of video card brand. Based on SOE's description, it sounds like the physics engine itself i being used, not the GPU-acceleration.
Video card brand will most likely not matter.
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